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DNA Lounge: a guide to San Francisco's longest-running independent club

DNA Lounge has run independently in SOMA since 1985. Two floors, goth and industrial weeks, queer nights, all-ages programming. The full guide.

Greenroom editorial / May 19, 2026

DNA Lounge has occupied 375 Eleventh Street in SOMA since 1985. Two floors, two stages, a small theatre upstairs, and a programming approach that has stayed open enough to hold goth, industrial, queer dance, indie rock, drag, burlesque, and weekend EDM under the same roof. Jamie Zawinski has owned it since 1999.

The programme runs almost every night. Monthly residencies hold most of the room's character: Death Guild on Monday (the country's longest-running weekly goth night), Bondage A Go-Go, Hubba Hubba Revue, Trannyshack, Soul of San Francisco. Touring acts fill the rest of the calendar.

The door

Open door, ticketed in advance for the bigger nights. Staff check IDs at the entrance, scan tickets, and refuse anyone visibly drunk or visibly aggressive. The club is one of the few all-ages-friendly rooms in the city, which means some nights are 18+ with wristbands at the bar.

What works at the door:

  • Tickets in advance through the DNA Lounge site. Most nights have a discount for advance buys.
  • ID. The staff check every time, even for over-21 wristbands.
  • Dressing for the night you came for. Death Guild expects black and leather. Bondage A Go-Go expects more of the same. EDM nights run more casual.
  • Cash or card.

What does not:

  • Visible drunkenness on arrival.
  • Trying to walk up to a sold-out night.
  • Aggressive behaviour at the door.
  • Bringing in outside drinks.

Death Guild runs walk-up every Monday. Bigger touring shows sell tickets in advance through the DNA site and DICE.

When to arrive

Doors are 9pm or 10pm for most weekend nights. The main floor peaks 11:30pm to 1:30am. The upstairs room runs its own programme on most nights and peaks slightly earlier.

Death Guild on Monday is a special case. The room fills around 10:30pm and runs deep into the night. For the dance floor at its fullest, aim for 11pm.

Inside

Two stages, two floors, a balcony around the main hall. The downstairs floor is the main dance space, with a proper concert rig that doubles as a club system. The upstairs room, Above DNA, runs its own programme: drag shows, burlesque, smaller touring acts, the occasional comedy night.

Programming character: a working monthly residency calendar with touring fills. Names that have run nights: the Death Guild residents (DJ Decay, DJ Melting Girl), Hubba Hubba Revue, the San Francisco drag circuit, plus regular touring industrial, EBM, post-punk, and goth bookings.

Phones are tolerated. The room has run a no-flash, please-respect-the-stage policy at certain shows. Mostly the staff lets the room manage itself.

What it costs

Cover is $5 to $20 for most nights. Touring shows run $25 to $45. Drinks are $9 to $14. Water at the bar is free. The pizza counter, when open, runs $4 to $7 a slice.

Rules

No aggression. No harassment. The room enforces consent on Bondage A Go-Go and the other adult-themed nights with explicit posted guidelines and floor staff who handle violations fast.

The room allows: dressing as far as you want for the themed nights, switching between the two floors, lingering at the bar after closing on slow nights, and bringing the costume you spent all day on without anyone batting an eye.

Why it matters

DNA Lounge is the room that survived. Forty years of San Francisco rent hikes, planning fights, license disputes, a 2008 closure, and the slow disappearance of the independent club. Jamie Zawinski has written publicly about how hard it has been to keep the doors open. The fact that the lights still come on every night is its own argument.

Beyond survival: the room held the goth and industrial scenes through their lean years, gave Death Guild a thirty-plus-year weekly home, kept the city's drag and burlesque scenes properly housed when other rooms cycled through ownership, and remained one of the only all-ages spaces in the city. It is the closest thing San Francisco has to a Berghain-style institution, which means: a room that protected something specific for long enough to matter.

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